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Eszopiclone

Packages:

Quantity Per Pill Price Order
200/1mg pills

Free EMS shipping with every order

$ 0.75 $150.00
100/1mg pills

Free EMS shipping with every order

$ 0.80 $80.00
50/1mg pills

Free EMS shipping with every order

$ 1.00 $50.00
300/1mg pills

Free EMS shipping with every order

$ 0.60 $180.00
600/1mg pills

Free EMS shipping with every order

$ 0.50 $299.00
50/2mg pills

Free EMS shipping with every order

$ 1.10 $55.00
100/2mg pills

Free EMS shipping with every order

$ 0.90 $90.00
200/2mg pills

Free EMS shipping with every order

$ 0.75 $150.00
300/2mg pills

Free EMS shipping with every order

$ 0.63 $190.00
600/2mg pills

Free EMS shipping with every order

$ 0.50 $299.00
50/3mg pills

Free EMS shipping with every order

$ 1.78 $89.00
100/3mg pills

Free EMS shipping with every order

$ 1.10 $110.00
200/3mg pills

Free EMS shipping with every order

$ 0.62 $125.00
300/3mg pills

Free EMS shipping with every order

$ 0.83 $250.00
600/3mg pills

Free EMS shipping with every order

$ 0.58 $350.00

Description:

Introduction

Eszopiclone, commonly known by its brand name Lunesta, is a prescription medication used to treat insomnia. It belongs to a class of drugs known as sedative-hypnotics, which are designed to help individuals fall asleep and maintain sleep throughout the night. Since its approval by the FDA in 2004, eszopiclone has become a widely used sleep aid, helping millions of people achieve a better night’s rest.

Mechanism of Action

Eszopiclone is an upgraded version of zopiclone. Eszopiclone works by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that promotes relaxation and induces sleep. GABA is the brain’s primary inhibitory neurotransmitter, and by increasing its effects, eszopiclone helps to calm the nervous system. Unlike benzodiazepines, another class of sedative-hypnotics, eszopiclone specifically targets GABA-A receptors, which are more involved in regulating sleep. This selective action is intended to minimize some of the side effects and dependency risks associated with broader-acting sedatives.

Therapeutic Uses of Eszopiclone

  1. Insomnia: Eszopiclone is primarily prescribed for the treatment of insomnia. It is effective in helping individuals fall asleep faster, reduce nighttime awakenings, and increase the total amount of sleep. It is particularly useful for people who have difficulty maintaining sleep or who wake up too early and struggle to fall back asleep.
  2. Chronic Sleep Issues: For individuals suffering from long-term sleep difficulties, eszopiclone can be prescribed for extended periods, unlike some other sleep aids that are intended for short-term use only. This makes it a valuable option for chronic insomnia.
  3. Off-Label Uses: While eszopiclone is not approved for other uses, some clinicians may prescribe it off-label for conditions that involve sleep disturbances, such as anxiety or depression-related insomnia. However, such uses should be carefully monitored.

Dosage and Administration

Eszopiclone is available in tablet form, typically in doses of 1 mg, 2 mg, and 3 mg. The recommended starting dose is usually 1 mg, taken right before bedtime. Depending on the patient’s response and the severity of the insomnia, the dose can be adjusted to 2 mg or 3 mg. It is important to take eszopiclone only when planning to get a full night’s sleep (7-8 hours) to avoid next-day drowsiness or impaired functioning.

Benefits

  • Effective Sleep Induction and Maintenance: Eszopiclone is effective not only in helping people fall asleep but also in reducing nighttime awakenings and prolonging sleep duration.
  • Longer-Term Use: Unlike some other sleep medications that are recommended for short-term use, eszopiclone can be prescribed for longer periods, providing relief for those with chronic insomnia.
  • Rapid Onset: Drug typically starts working within 30 minutes, making it a good option for those who struggle to fall asleep quickly.

Side Effects and Precautions

While eszopiclone is generally well-tolerated, it can cause side effects, some of which may impact daily functioning. Common side effects include:

  • Drowsiness: Residual drowsiness the next day is one of the most reported side effects, particularly with higher doses.
  • Headache: Some users may experience mild to moderate headaches.
  • Unpleasant Taste: A metallic or bitter taste in the mouth is a distinctive side effect experienced by many eszopiclone users.
  • Dizziness: Dizziness or lightheadedness may occur, especially when first starting the medication or when the dose is increased.

More serious side effects can include complex sleep behaviors such as sleepwalking, sleep-driving, or engaging in other activities while not fully awake. These behaviors can be dangerous and may require discontinuation of the medication.

Dependency and Withdrawal of Eszopiclone

Like many sedative-hypnotics, eszopiclone carries a risk of dependency, especially with long-term use. Patients should use the lowest effective dose for the shortest duration possible to minimize this risk. If eszopiclone is discontinued abruptly after prolonged use, withdrawal symptoms such as anxiety, unusual dreams, or rebound insomnia may occur. It is essential to taper off the medication under the guidance of a healthcare provider rather than stopping it suddenly.

Special Considerations

  • Liver Impairment: Patients with liver impairment may require dose adjustments or additional monitoring, as eszopiclone is metabolized by the liver.
  • Pregnancy and Breastfeeding: The use of eszopiclone during pregnancy or breastfeeding should be carefully considered, as the risks and benefits need to be weighed. It is generally advised to avoid use unless absolutely necessary.
  • Elderly Patients: Older adults may be more sensitive to the effects of this medicine, including drowsiness and dizziness, which could increase the risk of falls. Lower doses and careful monitoring are recommended.

Conclusion

Eszopiclone offers an effective solution for individuals struggling with insomnia, particularly those with difficulty maintaining sleep throughout the night. Its targeted action on GABA-A receptors, combined with the option for longer-term use, makes it a versatile and valuable tool in the management of sleep disorders. However, like all medications, it comes with potential side effects and risks that must be carefully managed. Patients should work closely with their healthcare provider to determine the appropriate dosage and duration of treatment, ensuring that the benefits of eszopiclone outweigh the potential drawbacks. With proper use, this drug can significantly improve sleep quality and overall well-being for those affected by insomnia.